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Inflammation is a biological process directly involving the interaction of immune cells with local tissues [1], where immune cells like macrophages secrete cytokines to recruit other immune cells and initiate inflammation [2], and serves as a sign of immune cells fighting invaders [3].
Facts (11)
Sources
What are Cytokines? Types & Function - Cleveland Clinic my.clevelandclinic.org 3 facts
claimTumor necrosis factor (TNF) is a cytokine that helps regulate inflammation and signals immune cells to kill tumor cells.
claimCytokines signal cell activation by directing immune cells toward infection sites to fight germs and by heightening or lessening processes associated with inflammation.
claimInflammation serves as a sign that the body's immune cells are fighting invaders or healing tissue damage.
Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com 3 facts
claimCytokines are small secreted proteins that act as key modulators of inflammation and are produced in response to invading pathogens to stimulate, recruit, and proliferate immune cells.
claimCXC chemokines are primarily involved in recruiting immune cells to sites of inflammation and mediating homeostatic migration and homing of lymphocytes.
claimImmune cells communicate via cytokines, which control cell proliferation, differentiation, and function, and are involved in inflammation, hematopoiesis, neurogenesis, embryogenesis, and oncogenesis.
Causes of Inflammation and How It Affects Health chanzuckerberg.com 1 fact
claimInflammation is a complex biological process involving the interaction of various immune cells with local tissue environments.
Immunity In Depth | Linus Pauling Institute lpi.oregonstate.edu 1 fact
claimCytokines secreted by immune cells during the early stages of inflammation stimulate the liver to synthesize acute-phase proteins.
The Center for Inflammation Science and Systems Medicine wertheim.scripps.ufl.edu 1 fact
claimThe protective process of inflammation helps accommodate the influx of immune cells, reduces further tissue damage by limiting excessive usage, and prevents the threat from spreading throughout the body.
A Double-Edged Sword: Inflammation and Your Health - Cedars-Sinai cedars-sinai.org 1 fact
claimThe inflammatory process involves immune cells flooding a site to destroy foreign invaders and damaged tissue, followed by the recession of inflammation to allow for healing once pathogens are eliminated.
Parts of the Immune System | Children's Hospital of Philadelphia chop.edu 1 fact
claimThe secretion of cytokines by macrophages recruits other immune cells to the area, which leads to inflammation.