Knowledge Tree
Relations (1)
related 2.32 — strongly supporting 4 facts
The follicular phase is characterized by specific fluctuations in estradiol production and serum levels, as evidenced by the daily production rates [1] and the parallel rise of estradiol with follicle growth [2]. Furthermore, rising estradiol levels during the late follicular phase are responsible for physiological changes in cervical mucus [3] and vaginal epithelial cells [4].
Facts (4)
Sources
The Normal Menstrual Cycle and the Control of Ovulation - NCBI - NIH ncbi.nlm.nih.gov 4 facts
claimDuring the late follicular phase, rising estradiol levels cause cervical mucous to become clear, copious, elastic, and increase in quantity by 30-fold compared to the early follicular phase.
measurementThe daily production rate of estradiol in women is 36 µg during the early follicular phase, 380 µg during the preovulatory phase, and 250 µg during the mid-luteal phase.
claimDuring the late follicular phase, rising estradiol levels cause vaginal epithelial cells to become acidophilic and display pyknotic nuclei.
claimDuring the follicular phase, serum estradiol levels rise in parallel with the growth of follicle size and the increasing number of granulosa cells.