sleep ↔ Parkinson's disease

Relations (1)

related 2.32 — strongly supporting 4 facts

Sleep dysfunction is identified as a potential risk factor for Parkinson's disease [1], and individuals diagnosed with the condition frequently experience sleep disturbances such as increased latency and frequent awakenings [2]. Furthermore, the relationship is reinforced by the impact of Parkinson's medications on sleep [3] and clinical research examining how dopamine agonists affect sleep in these patients [4].

Facts (4)

Sources

Extent and Health Consequences of Chronic Sleep Loss and ... - NCBI ncbi.nlm.nih.gov Colten HR, Altevogt BM · National Academies Press 3 facts

referenceCantor CR and Stern MB reviewed the effects of dopamine agonists on sleep in patients with Parkinson’s disease, published in Neurology in 2002.

claimMedications used to treat Parkinson’s disease include monoamine oxidase-B inhibitors (selegiline), presynaptic releasing agents (amantadine, anticholinergic agents), and catechol-O-methyltransferase (COMT) inhibitors (hyoscyamine, benztropine), all of which may potentially affect sleep (Chrisp et al., 1991).

measurementIndividuals with Parkinson’s disease suffer from increased sleep latency and frequent awakenings, spending as much as 30 to 40 percent of the night awake.

Why Sleep Is Important for Brain Health - American Brain Foundation americanbrainfoundation.org American Brain Foundation 1 fact

claimSleep and circadian rhythm dysfunction, such as fragmented sleep or night wakings, may be a risk factor for neurodegenerative disorders like Alzheimer’s and Parkinson’s disease.