macrophages ↔ Cytotoxic T lymphocytes

Relations (1)

related 2.00 — strongly supporting 3 facts

Macrophages and cytotoxic T lymphocytes are both targets of the cytokine IL-4 as described in [1], and they are functionally linked through the regulatory activity of helper T cells which activate macrophages as noted in [2] and [3].

Facts (3)

Sources

The components of the immune system - Immunobiology - NCBI - NIH ncbi.nlm.nih.gov Janeway CA Jr, Travers P, Walport M · Garland Science 2 facts

claimT lymphocytes (T cells) consist of two main classes: cytotoxic T cells, which kill virus-infected cells, and a second class that activates other cells such as B cells and macrophages.

claimT lymphocytes (T cells) consist of two main classes: cytotoxic T cells, which kill virus-infected cells, and a second class that activates other cells, including B cells and macrophages.

Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com Thermo Fisher Scientific 1 fact

referenceIL-4 is classified as an adaptive immunity cytokine, is produced by Th cells, binds to the CD124 receptor, targets B cells, T cells, and macrophages, and functions in the proliferation of B and cytotoxic T cells, enhancement of MHC class II expression, and stimulation of IgG and IgE production.