gut microbiome ↔ inflammation

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related 0.50 — strongly supporting 5 facts

Inflammation and gut microbiome are interconnected as disruptions to the gut microbiome from antibiotics, antacids, and NSAIDs cause intestinal wall inflammation known as leaky gut, triggering body-wide chronic inflammation [1][2], while Akebia trifoliata pericarp extract ameliorates inflammation by modifying gut microbiota [3], and the Western diet impacts both [4].

Facts (5)

Sources

Chronic Inflammation - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov National Library of Medicine 2 facts

claimThe use of antibiotics, antacids, and NSAIDs should be minimized because they can harm the gut microbiome, causing inflammation in intestinal walls known as leaky gut, which releases toxins and triggers body-wide chronic inflammation.

claimMinimizing the intake of antibiotics, antacids, and NSAIDs is recommended to prevent chronic inflammation because these substances can harm the gut microbiome, causing inflammation in intestinal walls known as leaky gut, which releases toxins and triggers body-wide inflammation.

Medicinal plants: bioactive compounds, biological activities ... frontiersin.org Frontiers in Immunology 1 fact

claimAkebia trifoliata pericarp extract ameliorates inflammation by modulating NF-κB/MAPK signaling pathways and modifying gut microbiota, as reported by Wang et al. in 2019.

Unknown source 1 fact

claimResearchers discuss the impact of the Western diet on various aspects of human health, specifically metabolism, the gut microbiome, inflammation, and cardiovascular health.

Chronic inflammation in the etiology of disease across the life span nature.com Nature 1 fact

referenceGut microbiota-mediated inflammation in obesity is linked to gastrointestinal cancer, as discussed in a 2018 review in Nature Reviews Gastroenterology & Hepatology.