luteal phase ↔ estradiol

Relations (1)

related 2.81 — strongly supporting 6 facts

The luteal phase is characterized by the episodic secretion of estradiol [1], which exhibits a secondary rise during the mid-luteal phase [2] and is subject to regulation by progesterone [3] and FSH [4].

Facts (6)

Sources

The Normal Menstrual Cycle and the Control of Ovulation - NCBI - NIH ncbi.nlm.nih.gov Feingold KR, Adler RA, Ahmed SF · National Center for Biotechnology Information 6 facts

procedureProgesterone decreases the biologic activity of estradiol on the endometrium during the luteal phase by decreasing the concentration of estradiol receptors, increasing the enzymatic activity of 17β-hydroxysteroid dehydrogenase type II (which converts estradiol to estrone), and increasing the activity of estrone sulfotransferase.

claimThe secretion of progesterone and estradiol during the luteal phase is episodic and correlates closely with pulses of Luteinizing hormone (LH) secretion.

claimIncreasing follicle-stimulating hormone (FSH) levels during the late luteal phase lead to an increase in the number of FSH receptors and an increase in estradiol secretion by granulosa cells.

claimThe secretion of progesterone and estradiol during the luteal phase is episodic and correlates closely with pulses of LH secretion.

measurementThe daily production rate of estradiol in women is 36 µg during the early follicular phase, 380 µg during the preovulatory phase, and 250 µg during the mid-luteal phase.

claimThe secondary rise in estradiol during the mid-luteal phase parallels the rise of serum progesterone and 17α-hydroxyprogesterone levels.