cholesterol ↔ testosterone

Relations (1)

related 0.20 — supporting 2 facts

Testosterone is directly produced from cholesterol in the testes by Leydig cells stimulated by LH [1]. This process is analogous to cholesterol conversion into pregnenolone in the adrenal glands [2].

Facts (2)

Sources

Physiology, Male Reproductive System - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov National Library of Medicine 2 facts

claimLH stimulates Leydig cells in the interstitium of the testes to produce testosterone from cholesterol.

claimAdrenocorticotropic hormone (ACTH) stimulates the enzyme desmolase to convert cholesterol into pregnenolone in the adrenal glands, a process analogous to testosterone synthesis in the testes.