Relations (1)

related 1.00 — strongly supporting 1 fact

The brain is the biological site where the 5-HT2A receptor mediates an active coping strategy in response to adversity, as described in [1].

Facts (1)

Sources
Psychedelics, Sociality, and Human Evolution frontiersin.org Frontiers 1 fact
claimThe brain displays two different serotonin-mediated responses to adversity: a default response involving a passive coping strategy mediated by 5-HT1A receptor signaling, and an active coping strategy that provides an enhanced capacity for change mediated by 5-HT2A receptor signaling.