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related 2.00 — strongly supporting 3 facts
Ketamine is investigated as a therapeutic intervention for suicidal ideation, as evidenced by clinical trials evaluating its acute treatment efficacy [1], its anti-suicide effects in adult patients [2], and meta-analyses assessing the impact of single-dose administration [3].
Facts (3)
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The Montreal model: an integrative biomedical-psychedelic ... frontiersin.org 3 facts
referenceAbbar et al. conducted a double-blind, randomised, placebo-controlled trial published in the BMJ in 2022, which investigated the use of ketamine for the acute treatment of severe suicidal ideation.
referenceWilkinson et al. conducted a systematic review and individual participant data meta-analysis on the effect of a single dose of intravenous ketamine on suicidal ideation, published in the American Journal of Psychiatry in 2018.
referenceZhou et al. found that cognitive function mediates the anti-suicide effect of repeated intravenous ketamine in adult patients with suicidal ideation, as published in Frontiers in Psychiatry in 2022.