neutrophils ↔ interleukin-6

Relations (1)

related 2.00 — strongly supporting 3 facts

Neutrophils are related to interleukin-6 because they are capable of releasing this cytokine as part of their immune response [1], and interleukin-6 is also produced downstream following the activation of neutrophils by IL-17 [2].

Facts (3)

Sources

Chronic Inflammation - StatPearls - NCBI Bookshelf ncbi.nlm.nih.gov National Library of Medicine 1 fact

claimNeutrophils destroy antigens through phagocytosis and the release of reactive oxygen species and cytokines, including IL-1, IL-6, and TNF-α.

Pro-Inflammatory Cytokines Overview | Thermo Fisher Scientific - US thermofisher.com Thermo Fisher Scientific 1 fact

referenceIL-17 is classified as a pro-inflammatory cytokine, is produced by Th17 cells, binds to the IL-17R receptor, targets monocytes and neutrophils, and functions in recruiting monocytes and neutrophils to the site of infection and activating downstream cytokines and chemokines including IL-1, IL-6, IL-8, IL-21, TNF-beta, and MCP-1.

Immunity In Depth | Linus Pauling Institute lpi.oregonstate.edu Linus Pauling Institute 1 fact

measurementIn a randomized, double-blind, placebo-controlled trial involving 46 healthy older adults (ages 55 to 75 years), daily supplementation with 720 mg of EPA and 280 mg of DHA for 12 weeks had no effect on the numbers of neutrophils, monocytes, or macrophages, nor did it affect respiratory burst or the production of cytokines TNF-α, IL-1β, and IL-6.