Chemotherapy and targeted cancer therapy are both primary modalities used in cancer treatment that are frequently compared for their mechanisms of action, side effect profiles, and clinical efficacy [1], [2], [3]. They are often administered in combination to improve patient outcomes [4], [5], [6], [7] and share common potential side effects such as thyroid damage, heart problems, peripheral neuropathy, and vision changes [8], [9], [10], [11].