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related 2.00 — strongly supporting 3 facts
Testosterone is a key hormone measured in studies of the hypothalamic-pituitary-gonadal axis [1], and its fluctuations are used to analyze the seasonal influence on this specific physiological system {fact:1, fact:3}.
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Seasonal Changes of Serum Gonadotropins and Testosterone in ... frontiersin.org 3 facts
procedureThe study 'Seasonal Changes of Serum Gonadotropins and Testosterone in...' analyzed testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) measurements collected between January 2010 and January 2019 using Chemiluminescent Microparticle Immunoassay, excluding subjects with factors interfering with the hypothalamic-pituitary-gonadal axis.
claimThe study on seasonal changes of serum gonadotropins and testosterone in males concluded that there are biannual or circannual fluctuations of serum luteinizing hormone (LH) and testosterone, which suggests a seasonal influence on the pituitary-gonadal axis in humans.
claimThe study on seasonal changes of serum gonadotropins and testosterone in males identified several strengths: it evaluated a large number of men living at the same latitude over a long time-frame, excluded participants with known diseases affecting the hypothalamic-pituitary-gonadal axis, and measured both testosterone and gonadotropins serum levels.