Knowledge Tree
Relations (1)
related 2.81 — strongly supporting 5 facts
Aging and cardiovascular disease are linked by shared pathological processes such as chronic inflammation, often termed 'inflammageing' [1], and the accumulation of senescence-associated markers in cardiac cell lineages [2]. Furthermore, both conditions are connected through common contributors like clonal hematopoiesis [3], T cell immunosenescence [4], and systemic inflammation {fact:1, fact:5}.
Facts (5)
Sources
Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com 2 facts
referenceShirakawa and Sano reviewed T cell immunosenescence in the context of aging, obesity, and cardiovascular disease in the journal Cells in 2021.
referenceLibby, P. and Kobold, S. published a study in 2019 titled 'Inflammation: a common contributor to cancer, aging, and cardiovascular diseases-expanding the concept of cardio-oncology' in Cardiovascular Research, which posits inflammation as a common factor contributing to cancer, aging, and cardiovascular diseases.
Chronic inflammation in the etiology of disease across the life span nature.com 1 fact
claimFerrucci, L. and Fabbri, E. (2018) define 'inflammageing' as chronic inflammation associated with aging, cardiovascular disease, and frailty.
Editorial: Inflammation and chronic disease - Frontiers frontiersin.org 1 fact
claimClonal hematopoiesis connects aging and inflammation in the context of cardiovascular disease, as discussed by Jaiswal and Libby in 2020.
Should you be tested for inflammation? health.harvard.edu 1 fact
claimStamping out inflammation would not eliminate cardiovascular disease, cancer, dementia, or aging.