Knowledge Tree
Relations (1)
related 2.00 — strongly supporting 3 facts
Aging and longevity are intrinsically linked as biological processes, with FOXO proteins [1] and circadian rhythms [2] serving as key regulatory mechanisms for both. Furthermore, cellular senescence is a shared underlying factor that influences both aging and longevity outcomes [3].
Facts (3)
Sources
Cellular rejuvenation: molecular mechanisms and potential ... - Nature nature.com 2 facts
referenceCircadian timing is important for aging and longevity, according to Acosta-Rodriguez et al. in Nature Communications (2021).
referenceFOXO proteins play a role in aging and longevity, as detailed in the 2016 paper 'Long live FOXO: unraveling the role of FOXO proteins in aging and longevity' published in Aging Cell.
Cellular senescence: from homeostasis to pathological implications ... frontiersin.org 1 fact
claimThe article "Cellular senescence: from homeostasis to pathological implications and therapeutic strategies" addresses the topics of cellular senescence, cancer, m6A RNA methylation, aging, longevity, and inflammation.