Knowledge Tree
Relations (1)
related 2.00 — strongly supporting 3 facts
The relationship is established because Hypericum perforatum exhibits antimicrobial activity against Klebsiella pneumoniae as stated in [1], and climbing acacia and java cedar demonstrate antimicrobial activity specifically targeting Klebsiella pneumoniae through electrostatic interactions as described in [2].
Facts (3)
Sources
Medicinal plants: bioactive compounds, biological activities ... frontiersin.org 3 facts
claimHypericum perforatum (St. John’s wort), originating from Europe, Asia, and North Africa, demonstrated in vitro antibacterial activity against Pseudomonas aeruginosa, Escherichia coli, Enterococcus faecalis, Klebsiella oxytoca, Klebsiella pneumoniae, and Staphylococcus aureus.
referenceMustapha A, Al Sharksi AN, Eze UA, Samaila RK, Ukwah BN, Anyiam AF, et al. published a 2024 study in BioMed titled 'Phytochemical composition, in silico molecular docking analysis and antibacterial activity of Lawsonia inermis linn leaves extracts against extended spectrum beta-lactamases-producing strains of Klebsiella pneumoniae', which analyzes the antibacterial properties of Lawsonia inermis leaves.
claimThe antimicrobial activity of climbing acacia and java cedar against Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species is attributed to electrostatic interactions between positively charged secondary metabolites and negatively charged bacterial cell membranes.